I've never adhered to the idea of trans-humanism. Yet I do believe that the Singularity is coming, and that what will happen then will be truly dramatic and spectacular. I don't see it as some kind of phase, a transformation of humanity. Rather, I see it as its end.
It is possible that some humans will either be uploaded into machines, genetically modified or augmented with nanotechnology. But it will be an anecdotal event when compared to something as dramatic as the creation of an Artificial Intelligence.
If human beings are uploaded or augmented I don't think it is appropriate to call them human anymore. They will be something else, something new.